703

• Gene Symbol: ITK
• Gene Name: IL2 inducible T-cell kinase
• Gene Aliases: EMT, LPFS1, LYK, PSCTK2
• Chromosome Location: Chr.5: 157180896 - 157255185 on Build GRCh38
• UniGene ID: Hs.558348
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005546.3	NP_005537.3	17	3416
	XM_017009443.1	XP_016864932.1	15	3029
GenBank mRNA	AB209622.1	-	16	4919
	BX538196.1	-	5	2156
	D13720.1	-	17	3416

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

cytokine production
NK T cell differentiation
adaptive immune response
cellular defense response
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
activation of phospholipase C activity
interferon-gamma production
interleukin-4 production
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
T cell activation
regulation of cell proliferation
innate immune response
T cell receptor signaling pathway

Function(s)

non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
metal ion binding