70513

• Gene Symbol: Spry2
• Gene Name: sprouty homolog 2 (Drosophila)
• Gene Aliases: sprouty2
• Chromosome Location: Chr.14: 105891947 - 105896819 on Build GRCm38
• UniGene ID: Mm.489870
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Spry2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011897.3	NP_036027.1	2	656
GenBank mRNA	AF153084.1	-	1	373
	AF176905.1	-	2	659
	BC138768.1	-	1	408	8861790
	BC138771.1	-	1	408	8861793

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012046, XM_006252438, BC089116.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
multicellular organism development
sensory perception of sound
negative regulation of cell proliferation
regulation of signal transduction
positive regulation of gene expression
negative regulation of peptidyl-threonine phosphorylation
lung development
positive regulation of peptidyl-serine phosphorylation
negative regulation of GTPase activity
negative regulation of fibroblast growth factor receptor signaling pathway
inner ear morphogenesis
negative regulation of apoptotic process
negative regulation of MAP kinase activity
cell fate commitment
negative regulation of Ras protein signal transduction
branching morphogenesis of an epithelial tube
negative regulation of neurotrophin TRK receptor signaling pathway
positive regulation of protein kinase B signaling
lung morphogenesis
lung growth
bud elongation involved in lung branching
respiratory system development
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity

Function(s)

protein binding
protein kinase binding
protein serine/threonine kinase activator activity