70889

• Gene Symbol: Ern2
• Gene Name: endoplasmic reticulum (ER) to nucleus signalling 2
• Gene Aliases: Ern1, Ire1, Ire1b
• Chromosome Location: Chr.7: 122169745 - 122186226 on Build GRCm38
• UniGene ID: Mm.20452
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ern2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012016.2	NP_036146.2	22	2908
GenBank mRNA	AF071777.1	-	22	2867
	AK139291.1	-	22	2893

More Information

Panther Classification:

Molecular Function -

endoribonuclease

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
protein phosphorylation
apoptotic process
response to unfolded protein
cell cycle arrest
activation of JUN kinase activity
metabolic process
rRNA catabolic process
phosphorylation
apoptotic chromosome condensation
response to endoplasmic reticulum stress
negative regulation of transcription, DNA-templated
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleotide binding
magnesium ion binding
catalytic activity
endonuclease activity
ribonuclease activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
bidentate ribonuclease III activity
transferase activity
transferase activity, transferring phosphorus-containing groups
hydrolase activity
metal ion binding