70892

• Gene Symbol: Aifm1
• Gene Name: apoptosis-inducing factor, mitochondrion-associated 1
• Gene Aliases: AIF, AIFsh2, Hq, Pdcd8
• Chromosome Location: Chr.X: 48474944 - 48513563 on Build GRCm38
• UniGene ID: Mm.240434
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Aifm1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290364.1	NP_001277293.1	11, 12	1382
	NM_012019.3	NP_036149.1	11, 12	1394
GenBank mRNA	AF100927.1	-	11, 12	1220
	AK133764.1	-	11, 12	1234
	AK165762.1	-	1, 2	185
	BC003292.1	-	11, 12	1257	3500037
	BC024882.1	-	11, 12	1878
	DQ016499.1	-	10, 11	2521

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_145812, NM_001130846, NM_145813, NM_004208, NM_001130847, and others.
This siRNA also targets the following transcripts in Rat: NM_031356, AF375656, BC072697, AB041723, AY787821.

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of cell death
neuron differentiation
mitochondrial respiratory chain complex I assembly
positive regulation of apoptotic process
cell redox homeostasis
neuron apoptotic process
oxidation-reduction process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
regulation of apoptotic DNA fragmentation

Function(s)

C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
DNA binding
aldo-keto reductase (NADP) activity
electron-transferring-flavoprotein dehydrogenase activity
isocitrate dehydrogenase activity
mevaldate reductase activity
protein binding
gluconate dehydrogenase activity
NAD(P)H oxidase activity
steroid dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on NAD(P)H
epoxide dehydrogenase activity
5-exo-hydroxycamphor dehydrogenase activity
2-hydroxytetrahydrofuran dehydrogenase activity
acetoin dehydrogenase activity
phenylcoumaran benzylic ether reductase activity
D-xylose:NADP reductase activity
L-arabinose:NADP reductase activity
D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
steroid dehydrogenase activity, acting on the CH-CH group of donors
(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
3-hydroxymenthone dehydrogenase activity
very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
dihydrotestosterone 17-beta-dehydrogenase activity
(R)-2-hydroxyisocaproate dehydrogenase activity
L-arabinose 1-dehydrogenase (NADP+) activity
L-xylulose reductase (NAD+) activity
protein dimerization activity
3-ketoglucose-reductase activity
flavin adenine dinucleotide binding
(R)-2-hydroxyglutarate dehydrogenase activity
D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity
FAD binding