70952

• Gene Symbol: Btk
• Gene Name: Bruton agammaglobulinemia tyrosine kinase
• Gene Aliases: AI528679, xid
• Chromosome Location: Chr.X: 134542334 - 134583623 on Build GRCm38
• UniGene ID: Mm.4475
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Btk
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013482.2	NP_038510.2	14	1485
GenBank mRNA	BC053392.1	-	14	1421	30075322
	L08967.1	-	14	1461
	L10627.1	-	14	1496
	L29788.1	-	14	1457

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001007798, FQ215667, AY787790.

Gene Ontology Categories:

Process(es)

adaptive immune response
immune system process
histamine secretion by mast cell
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
transmembrane receptor protein tyrosine kinase signaling pathway
I-kappaB kinase/NF-kappaB signaling
response to organic substance
phosphorylation
peptidyl-tyrosine phosphorylation
cell differentiation
cellular response to reactive oxygen species
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
protein autophosphorylation
cell maturation
B cell receptor signaling pathway
cellular response to molecule of fungal origin

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
lipid binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
identical protein binding
metal ion binding