71308

• Gene Symbol: Tcf4
• Gene Name: transcription factor 4
• Gene Aliases: 5730422P05Rik, ASP-I2, E2-2, E2.2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, SEF-2, SEF2, SEF2-1, TFE, Tcf-4, bHLHb19
• Chromosome Location: Chr.18: 69344490 - 69687967 on Build GRCm38
• UniGene ID: Mm.4269
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tcf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001083967.1	NP_001077436.1	4, 5	453
	NM_013685.2	NP_038713.1	4, 5	768
GenBank mRNA	AK028748.1	-	4, 5	379
	AK051958.1	-	3, 4	676
	AK081012.1	-	4, 5	405
	AK133885.1	-	5, 6	1180
	AK145285.1	-	4, 5	401
	BC043050.1	-	3, 4	228	5708370
	S75870.1	-	4, 5	340
	U16322.1	-	4, 5	740
	X91753.1	-	4, 5	392

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003199, NM_001243226, NM_001243231, NM_001243227, NM_001243230, and others.
This siRNA also targets the following transcripts in Rat: NM_053369, AF149284.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
multicellular organism development
nervous system development
cell differentiation
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein-DNA complex assembly

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, TFIIB-class binding
TFIIB-class transcription factor binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
protein C-terminus binding
protein homodimerization activity
bHLH transcription factor binding
protein heterodimerization activity
protein dimerization activity
E-box binding