71356

• Gene Symbol: Pnp
• Gene Name: purine-nucleoside phosphorylase
• Gene Aliases: AL024301, AU015798, Np, Np-1, Np-2, Pnp1
• Chromosome Location: Chr.14: 50944303 - 50953412 on Build GRCm38
• UniGene ID: Mm.17932
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pnp
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013632.4	NP_038660.1	2	420
GenBank mRNA	AK049817.1	-	2	199
	AK153451.1	-	2	422
	BC003788.1	-	2	192	3600212
	BC052679.1	-	2	171	30062908
	CT010254.1	-	1	140
	CT010316.1	-	1	140
	L11290.1	-	2	161
	L11291.1	-	2	161
	M84563.1	-		218
	U35374.1	-	1	140
	X56548.1	-	2	217

More Information

Panther Classification:

Molecular Function -

kinase, nucleotide kinase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
nucleobase-containing compound metabolic process
inosine catabolic process
deoxyinosine catabolic process
deoxyguanosine catabolic process
GTP biosynthetic process
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
nucleoside metabolic process
response to gamma radiation
urate biosynthetic process
positive regulation of T cell proliferation
purine nucleoside metabolic process
purine-containing compound salvage
positive regulation of B cell differentiation
positive regulation of DNA repair
dGTP metabolic process
guanosine catabolic process
positive regulation of alpha-beta T cell differentiation
negative regulation of T cell apoptotic process

Function(s)

nucleoside binding
purine nucleobase binding
catalytic activity
purine-nucleoside phosphorylase activity
drug binding
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring pentosyl groups
phosphate ion binding