71447

Gene Symbol:

Pnp Pnp2

Gene Name:

purine-nucleoside phosphorylase

purine-nucleoside phosphorylase 2

Gene Aliases:

AL024301, AU015798, Np, Np-1, Np-2, Pnp1

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Chromosome Location:

Chr.14: 50944303 - 50953412 on Build GRCm38

Chromosome Location:

Chr.14: 50956141 - 50964749 on Build GRCm38

UniGene ID:

Mm.17932

Mm.482171

Species:

Mouse

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: Pnp
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013632.4	NP_038660.1	6	1106
GenBank mRNA	AK049817.1	-	6	885
	AK153451.1	-	6	1108
	BC003788.1	-	6	878	3600212
	BC052679.1	-	6	857	30062908
	CT010254.1	-	5	826
	CT010316.1	-	5	826
	L11290.1	-	6	847
	L11291.1	-	6	847
	M84563.1	-		904
	U35374.1	-	5	826
	X56548.1	-	6	903

Gene Symbol: Pnp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001123371.2	NP_001116843.1	6	903
GenBank mRNA	AK008143.1	-	6	907

More Information

Panther Classification:

Molecular Function -

kinase, nucleotide kinase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
nucleobase-containing compound metabolic process
inosine catabolic process
deoxyinosine catabolic process
deoxyguanosine catabolic process
GTP biosynthetic process
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
nucleoside metabolic process
response to gamma radiation
urate biosynthetic process
positive regulation of T cell proliferation
purine nucleoside metabolic process
purine-containing compound salvage
positive regulation of B cell differentiation
positive regulation of DNA repair
dGTP metabolic process
guanosine catabolic process
positive regulation of alpha-beta T cell differentiation
negative regulation of T cell apoptotic process
biological_process

Function(s)

nucleoside binding
purine nucleobase binding
catalytic activity
purine-nucleoside phosphorylase activity
drug binding
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring pentosyl groups
phosphate ion binding