71854

• Gene Symbol: Heyl
• Gene Name: hairy/enhancer-of-split related with YRPW motif-like
• Gene Aliases: Hey3, Hrt3, bHLHb33, hesr3
• Chromosome Location: Chr.4: 123233556 - 123249870 on Build GRCm38
• UniGene ID: Mm.103615
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Heyl
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013905.3	NP_038933.2	2, 3	464
GenBank mRNA	AB093590.1	-	2, 3	156
	AF172288.1	-	2, 3	464
	AJ271868.2	-	2, 3	464
	AK004697.2	-	2, 3	167
	AK028596.1	-	2, 3	203
	AK080822.1	-	2, 3	168
	BC130263.1	-	2, 3	172	40142873

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_014571, AF311885, AJ272215, BC006087, AK300463, and others.
This siRNA also targets the following transcripts in Rat: NM_001107977.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
atrioventricular valve morphogenesis
pulmonary valve morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
endocardial cushion morphogenesis
cardiac ventricle morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
peripheral nervous system development
negative regulation of gene expression
mesenchymal cell development
skeletal muscle cell differentiation
positive regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cardiac epithelial to mesenchymal transition
ventricular septum morphogenesis
negative regulation of androgen receptor signaling pathway
negative regulation of androgen receptor activity

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, protein binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription corepressor activity
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
microsatellite binding
protein homodimerization activity
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity
AF-1 domain binding