71948

• Gene Symbol: Hey2
• Gene Name: hairy/enhancer-of-split related with YRPW motif 2
• Gene Aliases: CHF1, Herp1, Hrt2, bHLHb32, hesr2
• Chromosome Location: Chr.10: 30832359 - 30842783 on Build GRCm38
• UniGene ID: Mm.103573
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hey2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013904.1	NP_038932.1	2, 3	298
GenBank mRNA	AB093589.1	-	2, 3	166
	AF172287.1	-	2, 3	298
	AF173902.1	-	2, 3	290
	AF232240.1	-	2, 3	294
	AJ271867.1	-	2, 3	298
	AK031506.1	-	2, 3	145
	AK158000.1	-	2, 3	299
	BC103575.1	-	2, 3	238	40045790
	BC103576.1	-	2, 3	241	40045791
	BC105651.1	-	2, 3	238	40046419
	BC105652.1	-	2, 3	241	40046420

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_130417.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
vasculogenesis
muscular septum morphogenesis
outflow tract morphogenesis
atrioventricular valve development
pulmonary valve morphogenesis
tricuspid valve morphogenesis
tricuspid valve formation
endocardial cushion to mesenchymal transition involved in heart valve formation
cardiac ventricle morphogenesis
cardiac left ventricle morphogenesis
cardiac right ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
cardiac muscle hypertrophy
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
pattern specification process
anterior/posterior axis specification
positive regulation of heart rate
regulation of gene expression
negative regulation of gene expression
negative regulation of cardiac muscle cell apoptotic process
mesenchymal cell development
cardiac muscle hypertrophy in response to stress
ascending aorta morphogenesis
dorsal aorta morphogenesis
umbilical cord morphogenesis
cell fate commitment
regulation of auditory receptor cell differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle cell development
positive regulation of cardiac muscle cell proliferation
cardiac epithelial to mesenchymal transition
heart trabecula formation
cardiac septum morphogenesis
ventricular septum morphogenesis
atrial septum morphogenesis
negative regulation of transcription initiation from RNA polymerase II promoter
labyrinthine layer blood vessel development
artery development
arterial endothelial cell differentiation
cardiac vascular smooth muscle cell development
coronary vasculature morphogenesis
pulmonary artery morphogenesis
Notch signaling involved in heart development
protein-DNA complex assembly
cochlea development
negative regulation of transcription regulatory region DNA binding
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
regulation of vasculogenesis

Function(s)

transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, protein binding
RNA polymerase II activating transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
microsatellite binding
histone deacetylase binding
sequence-specific DNA binding
protein dimerization activity