72093

• Gene Symbol: Txnrd1
• Gene Name: thioredoxin reductase 1
• Gene Aliases: TR, TR1, TrxR1
• Chromosome Location: Chr.10: 82833951 - 82897724 on Build GRCm38
• UniGene ID: Mm.210155
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Txnrd1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042513.1	NP_001035978.1	3, 4	333
	NM_001042514.1	NP_001035979.1	2, 3	421
	NM_001042523.1	NP_001035988.1	3, 4	550
	NM_015762.2	NP_056577.2	2, 3	226
GenBank mRNA	AB027565.1	-	2, 3	253
	AF333036.1	-	3, 4	550
	AK011902.1	-	3, 4	334
	AK146125.1	-	2, 3	227
	AK149625.1	-	3, 4	334
	AK151927.1	-	3, 4	334
	AK168356.1	-	3, 4	334
	AK172383.1	-	2, 3	259
	AK177272.1	-	2, 3	153
	AK180432.1	-	2, 3	153
	AK184063.1	-	2, 3	153
	AK185936.1	-	2, 3	153
	AK186760.1	-	2, 3	173
	AK186897.1	-	2, 3	173
	AK194169.1	-	2, 3	171
	AK210892.1	-	2, 3	153
	BC020274.1	-	2, 3	188
	BC037643.1	-	2, 3	506	5059831
	CJ136679.1	-	3, 4	334
	CX562215.1	-	2, 3	421

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031614, BC085726, AF108213, AF220760, AF220761, and others.

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

mesoderm formation
response to oxidative stress
gastrulation
cell proliferation
positive regulation of cell death
selenocysteine metabolic process
benzene-containing compound metabolic process
hydrogen peroxide catabolic process
cell redox homeostasis
protein tetramerization
oxidation-reduction process
NADPH oxidation

Function(s)

thioredoxin-disulfide reductase activity
NAD(P)H oxidase activity
oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
selenate reductase activity
protein homodimerization activity
mercury ion binding
flavin adenine dinucleotide binding