7257

• Gene Symbol: GJA5
• Gene Name: gap junction protein alpha 5
• Gene Aliases: ATFB11, CX40
• Chromosome Location: Chr.1: 147756199 - 147781127 on Build GRCh38
• UniGene ID: Hs.447968
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GJA5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005266.6	NP_005257.2	2	299
	NM_181703.3	NP_859054.1	2	296
	XM_005272951.4	XP_005273008.1	2	649
	XM_017001044.1	XP_016856533.1	3	2338
GenBank mRNA	BC013313.2	-	2	267	3844139
	BQ231177.1	-	2	275
	BQ924948.1	-	2	291
	BT019415.1	-	1	155
	BT019416.1	-	1	155
	BX377692.2	-	2	296
	DR003194.1	-	2	299
	KJ534844.1	-	1	155

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019280, XM_008761328, BC070935, M83092, AF021806.

Panther Classification:

Molecular Function -

gap junction

Gene Ontology Categories:

Process(es)

skeletal system development
angiogenesis
negative regulation of glomerular filtration
outflow tract morphogenesis
endothelium development
cardiac conduction system development
mitral valve development
pulmonary valve formation
ventricular septum development
atrial septum development
septum primum development
atrial ventricular junction remodeling
potassium ion transport
cell communication by chemical coupling
positive regulation of cell communication by chemical coupling
gap junction assembly
embryonic limb morphogenesis
embryonic heart tube development
foramen ovale closure
negative regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of vasodilation
artery morphogenesis
protein oligomerization
transmembrane transport
regulation of cardiac muscle contraction
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
ventricular septum morphogenesis
atrial septum morphogenesis
ventricular cardiac muscle cell action potential
SA node cell action potential
AV node cell to bundle of His cell communication by electrical coupling
bundle of His cell to Purkinje myocyte communication by electrical coupling
cell communication by electrical coupling involved in cardiac conduction
regulation of heart rate by cardiac conduction
regulation of AV node cell action potential
regulation of bundle of His cell action potential
regulation of Purkinje myocyte action potential
regulation of atrial cardiac muscle cell action potential
regulation of renin secretion into blood stream
regulation of membrane depolarization during cardiac muscle cell action potential
vasomotion

Function(s)

gap junction hemi-channel activity
connexin binding
gap junction channel activity involved in cardiac conduction electrical coupling
gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling