72629

• Gene Symbol: Itgb3
• Gene Name: integrin beta 3
• Gene Aliases: CD61, GP3A, INGRB3
• Chromosome Location: Chr.11: 104608000 - 104670490 on Build GRCm38
• UniGene ID: Mm.87150
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Itgb3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016780.2	NP_058060.2	5, 6	856
GenBank mRNA	AF026509.1	-	5, 6	800
	AK157958.1	-	5, 6	802
	BC125518.1	-	5, 6	856	40130033
	BC125520.1	-	5, 6	856	40130035

More Information

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

positive regulation of endothelial cell proliferation
positive regulation of leukocyte migration
protein folding
cellular calcium ion homeostasis
cell-substrate junction assembly
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of endothelial cell migration
negative regulation of macrophage derived foam cell differentiation
positive regulation of fibroblast migration
negative regulation of lipid storage
smooth muscle cell migration
positive regulation of smooth muscle cell migration
cell growth
cell migration
platelet activation
regulation of cell migration
positive regulation of cell migration
cell-substrate adhesion
activation of protein kinase activity
negative regulation of lipid transport
positive regulation of cell adhesion mediated by integrin
positive regulation of osteoblast proliferation
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
apolipoprotein A-I-mediated signaling pathway
positive regulation of MAPK cascade
positive regulation of osteoclast differentiation
negative regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of angiogenesis
positive regulation of bone resorption
viral entry into host cell
positive regulation of smooth muscle cell proliferation
cell projection morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipoprotein metabolic process
negative chemotaxis
regulation of release of sequestered calcium ion into cytosol
angiogenesis involved in wound healing
negative regulation of cell death
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
positive regulation of glomerular mesangial cell proliferation
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

Function(s)

fibronectin binding
protease binding
protein disulfide isomerase activity
receptor activity
integrin binding
protein binding
peptide binding
identical protein binding
vascular endothelial growth factor receptor 2 binding
cell adhesion molecule binding
extracellular matrix binding
fibrinogen binding