73527

• Gene Symbol: Ppp2ca
• Gene Name: protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
• Gene Aliases: PP2A, R75353
• Chromosome Location: Chr.11: 52098824 - 52122749 on Build GRCm38
• UniGene ID: Mm.260288
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ppp2ca
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019411.4	NP_062284.1	1, 2	335
GenBank mRNA	AF076192.1	-	1, 2	305
	AK076110.1	-	1, 2	336
	AK172644.1	-	1, 2	308
	AK195960.1	-	1, 2	117
	BC003856.1	-	1, 2	312	3484084
	BC054458.1	-	1, 2	295	6493866
	Z67745.1	-	1, 2	110

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002715, BC002657, J03804, X12646, CR457417, and others.
This siRNA also targets the following transcripts in Rat: NM_017039, XM_008773894, BC070914, X14159, BC072531, and others.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of protein phosphorylation
negative regulation of protein phosphorylation
protein dephosphorylation
mesoderm development
regulation of receptor activity
negative regulation of epithelial to mesenchymal transition
regulation of protein autophosphorylation
positive regulation of protein phosphatase type 2A activity
positive regulation of protein dephosphorylation
regulation of protein catabolic process
negative regulation of transcription factor import into nucleus
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
meiotic cell cycle
regulation of cell cycle
protein heterotrimerization
cellular response to glucose stimulus
positive regulation of protein serine/threonine kinase activity
negative regulation of calcium ion transmembrane transporter activity

Function(s)

phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein binding
protein C-terminus binding
hydrolase activity
enzyme binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
protein complex binding
protein kinase B binding
ion channel binding
metal ion binding
protein dimerization activity
tau protein binding
GABA receptor binding
protein phosphatase 2A binding
protein antigen binding