738

• Gene Symbol: MAP3K5
• Gene Name: mitogen-activated protein kinase kinase kinase 5
• Gene Aliases: ASK1, MAPKKK5, MEKK5
• Chromosome Location: Chr.6: 136557046 - 136793098 on Build GRCh38
• UniGene ID: Hs.186486
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP3K5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005923.3	NP_005914.1	12	2161
	XM_011535839.2	XP_011534141.2	13	2485
	XM_017010870.1	XP_016866359.1	13	2484
	XM_017010871.1	XP_016866360.1	13	2484
	XM_017010872.1	XP_016866361.1	13	2483
	XM_017010873.1	XP_016866362.1	13	2482
	XM_017010874.1	XP_016866363.1	12	2376
	XM_017010875.1	XP_016866364.1	12	2375
	XM_017010876.1	XP_016866365.1	11	1492
	XM_017010877.1	XP_016866366.1	11	1729
GenBank mRNA	AB209093.1	-	12	2265
	AK293953.1	-	12	1421
	AK294507.1	-	3	277
	BC054503.2	-	12	2108	6143181
	BC088829.1	-	12	2162	6007002
	D84476.2	-	12	2067
	U67156.1	-	12	2160

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to ischemia
protein phosphorylation
JNK cascade
activation of JUN kinase activity
intrinsic apoptotic signaling pathway in response to oxidative stress
viral process
response to endoplasmic reticulum stress
p38MAPK cascade
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of JUN kinase activity
innate immune response
positive regulation of myoblast differentiation
positive regulation of JNK cascade
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to hydrogen peroxide
apoptotic signaling pathway
programmed necrotic cell death
positive regulation of neuron death
cellular response to reactive nitrogen species

Function(s)

magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity