73927

• Gene Symbol: Wwox
• Gene Name: WW domain-containing oxidoreductase
• Gene Aliases: 5330426P09Rik, 9030416C10Rik, WOX1
• Chromosome Location: Chr.8: 114439630 - 115352712 on Build GRCm38
• UniGene ID: Mm.440420
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wwox
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019573.3	NP_062519.2	4	503
GenBank mRNA	AF187014.1	-	4	454
	AK018507.1	-	4	433
	AK019911.1	-	4	461
	AK046903.1	-	4	453
	AK050541.1	-	4	455
	AK078528.1	-	4	456
	AK083096.1	-	4	435
	BC014716.1	-	4	459	4241066

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106188, XM_006255673, XM_006255666, XM_008772491, XM_006255670, and others.

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

osteoblast differentiation
apoptotic process
metabolic process
Wnt signaling pathway
negative regulation of Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter
skeletal system morphogenesis
oxidation-reduction process
cellular response to transforming growth factor beta stimulus
intrinsic apoptotic signaling pathway by p53 class mediator
extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
RNA polymerase II transcription coactivator activity
aldo-keto reductase (NADP) activity
isocitrate dehydrogenase activity
mevaldate reductase activity
protein binding
gluconate dehydrogenase activity
steroid dehydrogenase activity
oxidoreductase activity
epoxide dehydrogenase activity
5-exo-hydroxycamphor dehydrogenase activity
2-hydroxytetrahydrofuran dehydrogenase activity
acetoin dehydrogenase activity
enzyme binding
phenylcoumaran benzylic ether reductase activity
D-xylose:NADP reductase activity
L-arabinose:NADP reductase activity
D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
steroid dehydrogenase activity, acting on the CH-CH group of donors
(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
3-hydroxymenthone dehydrogenase activity
very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
dihydrotestosterone 17-beta-dehydrogenase activity
(R)-2-hydroxyisocaproate dehydrogenase activity
L-arabinose 1-dehydrogenase (NADP+) activity
L-xylulose reductase (NAD+) activity
3-ketoglucose-reductase activity
(R)-2-hydroxyglutarate dehydrogenase activity
D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity