7414

• Gene Symbol: FKBP1B
• Gene Name: FK506 binding protein 1B
• Gene Aliases: FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase
• Chromosome Location: Chr.2: 24033205 - 24067743 on Build GRCh38
• UniGene ID: Hs.709461
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FKBP1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001322963.1	NP_001309892.1	5	776
	NM_001322964.1	NP_001309893.1	4	595
	NM_004116.4	NP_004107.1	4	708
	NM_054033.3	NP_473374.1	4	753
	NR_136536.1		6	910
	NR_136538.1		5	842
	NR_136539.1		4	640
	XM_017003593.1	XP_016859082.1	6	811
	XM_017003594.1	XP_016859083.1	4	575
	XM_017003595.1	XP_016859084.1	3	556
	XM_017003596.1	XP_016859085.1	5	802
GenBank mRNA	BC002614.1	-	4	696	3161896
	BU508033.1	-	4	672
	D38037.1	-	4	633
	L37086.1	-	4	625
	S69800.1	-	5	545
	S69815.1	-	4	629

More Information

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein peptidyl-prolyl isomerization
'de novo' protein folding
smooth muscle contraction
response to glucose
negative regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
neuronal action potential propagation
protein maturation by protein folding
insulin secretion
negative regulation of protein phosphatase type 2B activity
response to vitamin E
ion transmembrane transport
calcium-mediated signaling using intracellular calcium source
protein refolding
T cell proliferation
response to hydrogen peroxide
positive regulation of axon regeneration
negative regulation of release of sequestered calcium ion into cytosol
positive regulation of sequestering of calcium ion
regulation of cytosolic calcium ion concentration
response to redox state
regulation of ryanodine-sensitive calcium-release channel activity
negative regulation of ryanodine-sensitive calcium-release channel activity
chaperone-mediated protein folding
negative regulation of insulin secretion involved in cellular response to glucose stimulus
cell communication by electrical coupling involved in cardiac conduction
regulation of cardiac conduction

Function(s)

peptidyl-prolyl cis-trans isomerase activity
receptor binding
ryanodine-sensitive calcium-release channel activity
protein binding
FK506 binding
calcium channel inhibitor activity
cyclic nucleotide binding
ion channel binding