74307

• Gene Symbol: Foxo1
• Gene Name: forkhead box O1
• Gene Aliases: AI876417, Afxh, FKHR, Fkhr1, Foxo1a
• Chromosome Location: Chr.3: 52268337 - 52350109 on Build GRCm38
• UniGene ID: Mm.29891
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Foxo1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019739.3	NP_062713.2	2	1815
GenBank mRNA	AF114258.1	-	2	1733
	AF126056.1	-	2	1356
	AJ252157.1	-	2	1778
	AK053633.1	-	1	515
	AK137629.1	-	2	1763
	AK154041.1	-	2	1816

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191846, AF247812.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
autophagy
apoptotic process
cellular response to DNA damage stimulus
insulin receptor signaling pathway
cellular response to starvation
anatomical structure morphogenesis
positive regulation of autophagy
cell differentiation
cellular response to insulin stimulus
negative regulation of stress-activated MAPK cascade
cellular response to oxidative stress
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
regulation of cell proliferation
glucose homeostasis
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of fat cell differentiation
positive regulation of gluconeogenesis
positive regulation of protein catabolic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cellular response to hyperoxia
cellular response to nitric oxide
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
regulation of nucleic acid-templated transcription
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process

Function(s)

transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
ubiquitin protein ligase binding
sequence-specific DNA binding
protein phosphatase 2A binding