74349

• Gene Symbol: Tbk1
• Gene Name: TANK-binding kinase 1
• Gene Aliases: 1200008B05Rik, AI462036, AW048562
• Chromosome Location: Chr.10: 121546455 - 121586794 on Build GRCm38
• UniGene ID: Mm.34580
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tbk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019786.4	NP_062760.3	2, 3	243
GenBank mRNA	AF145705.1	-	1, 2	95
	AF191839.1	-	1, 2	122
	AK004649.2	-	2, 3	197
	AK083214.1	-	2, 3	190
	AK168193.1	-	2, 3	229
	BC129910.1	-	1, 2	155	40111752
	BC129911.1	-	1, 2	155	40111754
	BU708441.1	-	2, 3	236

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106786.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

activation of innate immune response
immune system process
protein phosphorylation
negative regulation of gene expression
phosphorylation
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
dendritic cell proliferation
innate immune response
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
defense response to Gram-positive bacterium
defense response to virus

Function(s)

nucleotide binding
nucleic acid binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphoprotein binding