74764

• Gene Symbol: Rabgef1
• Gene Name: RAB guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: Rab5ef, Rabex5, Rin2
• Chromosome Location: Chr.5: 130171791 - 130214342 on Build GRCm38
• UniGene ID: Mm.288639
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rabgef1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199059.1	NP_001185988.1	3	352
	NM_019983.2	NP_064367.1	2	497
GenBank mRNA	AF093590.1	-	3	328
	AK044568.1	-	2	517
	AK146734.1	-	3	302
	BC018229.1	-	2	497	4507477

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
transport
endocytosis
protein transport
protein ubiquitination
negative regulation of mast cell activation
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
metal ion binding
ubiquitin protein ligase activity