75384

• Gene Symbol: Cftr
• Gene Name: cystic fibrosis transmembrane conductance regulator
• Gene Aliases: AW495489, Abcc7
• Chromosome Location: Chr.6: 18170262 - 18322774 on Build GRCm38
• UniGene ID: Mm.15621
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cftr
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021050.2	NP_066388.1	14	1977
GenBank mRNA	M60493.1	-	14	1978
	M69298.1	-	14	1976
	X72693.1	-	4	306
	X72694.1	-	4	305

More Information

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

cholesterol biosynthetic process
transport
ion transport
chloride transport
water transport
bicarbonate transport
iodide transport
cholesterol transport
transepithelial chloride transport
lung development
vasodilation
positive regulation of vasodilation
sperm capacitation
intracellular pH elevation
transmembrane transport
membrane hyperpolarization
cellular response to cAMP
chloride transmembrane transport
positive regulation of voltage-gated chloride channel activity

Function(s)

nucleotide binding
chloride channel activity
channel-conductance-controlling ATPase activity
protein binding
ATP binding
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
hydrolase activity
ATPase activity
chloride channel inhibitor activity
enzyme binding
PDZ domain binding
ATPase activity, coupled to transmembrane movement of substances