7750

• Gene Symbol: A2M
• Gene Name: alpha-2-macroglobulin
• Gene Aliases: A2MD, CPAMD5, FWP007, S863-7
• Chromosome Location: Chr.12: 9067708 - 9115962 on Build GRCh38
• UniGene ID: Hs.212838
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: A2M
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000014.4	NP_000005.2	3	415
	XM_006719056.2	XP_006719119.1	3	393
GenBank mRNA	AB209614.2	-	3	326
	AK312482.1	-	3	316
	AY591530.1	-	3	380
	BC026246.1	-	3	371
	BC040071.1	-	3	354	6056126
	CR749334.1	-	3	373
	M11313.1	-	3	345

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of complement activation, lectin pathway
platelet degranulation
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
extracellular matrix disassembly
positive regulation of GTPase activity
stem cell differentiation
regulation of small GTPase mediated signal transduction

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
GTPase activator activity
receptor binding
protein binding
growth factor binding
enzyme binding
interleukin-8 binding
interleukin-1 binding
tumor necrosis factor binding
calcium-dependent protein binding