7760

• Gene Symbol: AGT
• Gene Name: angiotensinogen
• Gene Aliases: ANHU, SERPINA8
• Chromosome Location: Chr.1: 230702523 - 230714590 on Build GRCh38
• UniGene ID: Hs.19383
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: AGT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000029.3	NP_000020.1	2	1017
GenBank mRNA	AB209769.1	-	2	529
	AK222798.1	-	2	548
	AK222815.1	-	2	549
	AK303755.1	-	3	490
	AK307978.1	-	3	463
	AK312291.1	-	2	627
	BC011519.1	-	2	537	4213559
	BF338744.1	-	2	621
	BT006851.1	-	1	509
	K02215.1	-	2	548
	M69110.1	-	1	523

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

regulation of cell growth
positive regulation of cytokine production
kidney development
blood vessel remodeling
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
regulation of renal output by angiotensin
regulation of heart rate
regulation of blood vessel size by renin-angiotensin
renal system process
angiotensin-mediated drinking behavior
positive regulation of extracellular matrix constituent secretion
cellular sodium ion homeostasis
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
phospholipase C-activating G-protein coupled receptor signaling pathway
activation of phospholipase C activity
nitric oxide mediated signal transduction
cell-cell signaling
female pregnancy
aging
regulation of blood pressure
positive regulation of activation of JAK2 kinase activity
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol esterification
negative regulation of endopeptidase activity
regulation of norepinephrine secretion
positive regulation of phosphatidylinositol 3-kinase signaling
artery smooth muscle contraction
response to muscle activity involved in regulation of muscle adaptation
negative regulation of angiogenesis
regulation of vasoconstriction
negative regulation of cell growth
positive regulation of cellular protein metabolic process
positive regulation of superoxide anion generation
positive regulation of NAD(P)H oxidase activity
negative regulation of tissue remodeling
low-density lipoprotein particle remodeling
catenin import into nucleus
regulation of renal sodium excretion
positive regulation of renal sodium excretion
regulation of cell proliferation
vasodilation
positive regulation of nitric oxide biosynthetic process
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of blood pressure
positive regulation of transcription, DNA-templated
positive regulation of vasodilation
fibroblast proliferation
positive regulation of fibroblast proliferation
regulation of long-term neuronal synaptic plasticity
smooth muscle cell proliferation
cytokine secretion
positive regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of NF-kappaB transcription factor activity
negative regulation of neurotrophin TRK receptor signaling pathway
stress-activated MAPK cascade
regulation of calcium ion transport
regulation of transmission of nerve impulse
cell growth involved in cardiac muscle cell development
positive regulation of protein tyrosine kinase activity
ERK1 and ERK2 cascade
uterine smooth muscle contraction
cellular response to mechanical stimulus
positive regulation of branching involved in ureteric bud morphogenesis
regulation of extracellular matrix assembly
positive regulation of gap junction assembly
regulation of cardiac conduction
positive regulation of reactive oxygen species metabolic process
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

serine-type endopeptidase inhibitor activity
hormone activity
protein binding
growth factor activity
type 1 angiotensin receptor binding
type 2 angiotensin receptor binding