78446

• Gene Symbol: Aptx
• Gene Name: aprataxin
• Gene Aliases: 2410016G21Rik, AA388047, FHA-HIT
• Chromosome Location: Chr.4: 40682078 - 40721667 on Build GRCm38
• UniGene ID: Mm.430710
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Aptx
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025444.3	NP_001020615.1	4	325
	NM_001025445.2	NP_001020616.1	4	320
	NM_025545.4	NP_079821.3	4	460
GenBank mRNA	AK005286.1	-	3	277
	AK010516.1	-	4	307
	AK017522.1	-	3	290
	AK077351.1	-	4	461
	AY040780.1	-	4	471
	AY208844.1	-	4	472
	BC021872.1	-	4	318	3994375
	BC068309.1	-	3	233
	BC071213.1	-	4	312

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001195248, NM_175069, NM_001195251, NM_175073, NM_001195249, and others.
This siRNA also targets the following transcripts in Rat: NM_148889, XM_008763607, XM_006238028, XM_006238027, XM_006238026, and others.

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

single strand break repair
DNA ligation
DNA repair
double-strand break repair
cellular response to DNA damage stimulus
dephosphorylation
regulation of protein stability
response to hydrogen peroxide
nucleic acid phosphodiester bond hydrolysis
polynucleotide 3' dephosphorylation

Function(s)

DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
double-stranded RNA binding
catalytic activity
GPI-anchor transamidase activity
phosphoglycolate phosphatase activity
hydrolase activity
DNA 5'-adenosine monophosphate hydrolase activity
polynucleotide 3'-phosphatase activity
metal ion binding
protein N-terminus binding
phosphoprotein binding
coenzyme F390-A hydrolase activity
coenzyme F390-G hydrolase activity