79736

• Gene Symbol: Rffl
• Gene Name: ring finger and FYVE like domain containing protein
• Gene Aliases: 1700051E09Rik, 4930516L10Rik, BG080975, Carp2
• Chromosome Location: Chr.11: 82803819 - 82871239 on Build GRCm38
• UniGene ID: Mm.341608
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rffl
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007465.3	NP_001007466.1	3	516
	NM_001164569.1	NP_001158041.1	4	660
	NM_001164570.1	NP_001158042.1	4	602
	NM_001164571.1	NP_001158043.1	3	519
	NM_026097.3	NP_080373.1	3	627
GenBank mRNA	AF434814.1	-	2	305
	AK006757.1	-	3	616
	AK007189.1	-	3	615
	AK015806.1	-	3	628
	AK028095.1	-	3	616
	AK128983.1	-	4	603
	AK150213.1	-	3	449
	AK150541.1	-	4	622
	AK159442.1	-	3	475
	AK169393.1	-	3	460
	AK169988.1	-	3	517
	BC118517.1	-	3	402	40105713

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001017368, BC028424, AK308689, AF434816, CR933651, and others.
This siRNA also targets the following transcripts in Rat: NM_001004068, XM_006246973, XM_006246969, XM_008767954, XM_006246978, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
intracellular protein transport
apoptotic process
regulation of fibroblast migration
negative regulation of tumor necrosis factor-mediated signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein K48-linked ubiquitination
negative regulation of signal transduction by p53 class mediator
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

protease binding
p53 binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
protein kinase binding
ubiquitin protein ligase binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity