81099

• Gene Symbol: Tmbim6
• Gene Name: transmembrane BAX inhibitor motif containing 6
• Gene Aliases: 5031406P05Rik, Bi1, Tegt
• Chromosome Location: Chr.15: 99392947 - 99410049 on Build GRCm38
• UniGene ID: Mm.16769
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tmbim6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001171034.1	NP_001164505.1	7, 8	778
	NM_001171035.1	NP_001164506.1	6, 7	634
	NM_001171036.1	NP_001164507.1	7, 8	599
	NM_026669.4	NP_080945.1	6, 7	563
GenBank mRNA	AK019865.2	-	6, 7	525
	AK036782.1	-	6, 7	525
	AK036994.1	-	6, 7	525
	AK049604.1	-	6, 7	514
	AK050299.1	-	6, 7	526
	AK050323.1	-	6, 7	514
	AK088030.1	-	6, 7	525
	AK088683.1	-	6, 7	526
	AK139901.1	-	6, 7	526
	AK159380.1	-	6, 7	525
	AK166935.1	-	6, 7	525
	AK206236.1	-	1, 2	30
	BC005588.1	-	6, 7	508	3708463

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019381, XM_008765670, XM_006257323, AY325130, AY325243, and others.

Gene Ontology Categories:

Process(es)

apoptotic process
response to unfolded protein
negative regulation of mRNA cleavage
negative regulation of protein binding
endoplasmic reticulum calcium ion homeostasis
response to endoplasmic reticulum stress
negative regulation of apoptotic process
negative regulation of immunoglobulin secretion
negative regulation of endoribonuclease activity
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
response to L-glutamate
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
negative regulation of IRE1-mediated unfolded protein response
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
negative regulation of apoptotic signaling pathway

Function(s)

enzyme binding
ubiquitin protein ligase binding
endoribonuclease inhibitor activity