8118

• Gene Symbol: PRNP
• Gene Name: prion protein
• Gene Aliases: ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
• Chromosome Location: Chr.20: 4686151 - 4701588 on Build GRCh38
• UniGene ID: Hs.472010
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PRNP
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000311.3	NP_000302.1	2	787
	NM_001080121.1	NP_001073590.1	2	782
	NM_001080122.1	NP_001073591.1	2	778
	NM_001080123.1	NP_001073592.1	2	651
	NM_001271561.1	NP_001258490.1	2	787
	NM_183079.2	NP_898902.1	2	783
GenBank mRNA	AB300823.1	-	1	425
	AB300824.1	-	1	425
	AB300825.1	-	1	425
	AB300826.1	-	1	425
	AK090575.1	-	3	386
	AK293312.1	-	3	385
	AK295415.1	-	3	337
	AK295943.1	-	3	403
	AK312276.1	-	2	475
	AY008282.1	-	2	458
	AY569456.1	-	1	415
	BC012844.1	-	2	462	3863784
	BC022532.1	-	2	475	4813982
	BG397054.1	-		516
	BP251427.1	-	2	564
	BT019496.1	-	1	415
	CR542039.1	-	1	415
	CR542072.1	-	1	415
	D00015.1	-	1	467
	M13667.1	-	1	467
	M13899.1	-	2	464

More Information

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
cellular copper ion homeostasis
response to oxidative stress
cell cycle arrest
learning or memory
metabolic process
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-2 production
regulation of protein localization
cellular response to drug
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of activated T cell proliferation
response to cadmium ion
negative regulation of T cell receptor signaling pathway
protein homooligomerization
negative regulation of calcineurin-NFAT signaling cascade
cellular response to copper ion
regulation of potassium ion transmembrane transport

Function(s)

copper ion binding
protein binding
lamin binding
microtubule binding
tubulin binding
identical protein binding
ATP-dependent protein binding
ion channel binding
chaperone binding