81420

• Gene Symbol: Mlh1
• Gene Name: mutL homolog 1 (E. coli)
• Gene Aliases: 1110035C23Rik, AI317206, AI325952, AI561766
• Chromosome Location: Chr.9: 111228228 - 111271786 on Build GRCm38
• UniGene ID: Mm.486383
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mlh1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_026810.2	NP_081086.2	6	580
GenBank mRNA	AF250844.1	-	6	496
	AK038265.1	-	6	573
	AK145646.1	-	6	527
	AK168849.1	-	6	519
	BC021815.1	-	6	534	4020489

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008766652.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA poly(A) tail shortening
resolution of meiotic recombination intermediates
somatic recombination of immunoglobulin genes involved in immune response
DNA repair
mismatch repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
cell cycle
male meiosis chromosome segregation
meiotic nuclear division
synapsis
reciprocal meiotic recombination
male meiosis
spermatogenesis
intrinsic apoptotic signaling pathway in response to DNA damage
female meiosis chromosome segregation
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
meiotic metaphase I plate congression
meiotic chromosome segregation
homologous chromosome segregation
isotype switching
negative regulation of mitotic recombination
oogenesis
meiotic spindle midzone assembly

Function(s)

single-stranded DNA binding
ATP binding
ATPase activity
mismatched DNA binding
guanine/thymine mispair binding
MutSalpha complex binding
structure-specific DNA binding