8189

• Gene Symbol: OCRL
• Gene Name: OCRL, inositol polyphosphate-5-phosphatase
• Gene Aliases: INPP5F, LOCR, NPHL2, OCRL-1, OCRL1
• Chromosome Location: Chr.X: 129532737 - 129592561 on Build GRCh38
• UniGene ID: Hs.126357
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: OCRL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000276.3	NP_000267.2	3	317
	NM_001318784.1	NP_001305713.1	3	340
	NM_001587.3	NP_001578.2	3	317
	XM_005262422.2	XP_005262479.1	2	124
	XM_011531344.2	XP_011529646.1	2	108
	XM_011531345.2	XP_011529647.1	2	111
	XM_017029554.1	XP_016885043.1	3	248
GenBank mRNA	AK226116.1	-	3	340
	AK293107.1	-	3	316
	BC025253.2	-	3	228
	BC094726.1	-	3	321	30528571
	BC130612.1	-	3	261	40146643
	BC144106.1	-	3	261	9052626
	U57627.2	-	3	317

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108256, XM_006257529, XM_006257528.

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

in utero embryonic development
lipid metabolic process
phosphatidylinositol biosynthetic process
signal transduction
cilium assembly
regulation of GTPase activity
positive regulation of GTPase activity
inositol phosphate metabolic process
phosphatidylinositol dephosphorylation
regulation of small GTPase mediated signal transduction

Function(s)

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GTPase activator activity
protein binding
Rac GTPase binding
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
inositol phosphate phosphatase activity