81

• Gene Symbol: ACVR2B
• Gene Name: activin A receptor type 2B
• Gene Aliases: ACTRIIB, ActR-IIB, HTX4
• Chromosome Location: Chr.3: 38454299 - 38493142 on Build GRCh38
• UniGene ID: Hs.174273
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ACVR2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001106.3	NP_001097.2	2	257
	XM_005265583.3	XP_005265640.1	2	2719
	XM_017007514.1	XP_016863003.1	2	2698
	XM_017007515.1	XP_016863004.1	2	343
	XM_017007516.1	XP_016863005.1	2	3667
GenBank mRNA	AB209449.1	-	1	4022
	BC096243.1	-	2	237	40005760
	BC096244.1	-	2	237	40005761
	BC096245.1	-	2	237	40005763
	BC099642.4	-	2	237	40005762
	BP352716.1	-	2	220
	X77533.1	-	2	237

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031554, XM_006244072, BC097358, M87067.
This siRNA also targets the following transcripts in Mouse: NM_007397, BC106189, M84120, AK137432.

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
gastrulation with mouth forming second
kidney development
lymphangiogenesis
blood vessel remodeling
regulation of transcription, DNA-templated
signal transduction
transmembrane receptor protein serine/threonine kinase signaling pathway
determination of left/right symmetry
mesoderm development
heart development
response to glucose
post-embryonic development
anterior/posterior pattern specification
signal transduction by protein phosphorylation
insulin secretion
lung development
positive regulation of bone mineralization
BMP signaling pathway
pancreas development
activation of protein kinase activity
activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
organ growth
odontogenesis of dentin-containing tooth
positive regulation of osteoblast differentiation
embryonic foregut morphogenesis
skeletal system morphogenesis
palate development
lymphatic endothelial cell differentiation
artery development
venous blood vessel development
retina vasculature development in camera-type eye

Function(s)

protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
activin receptor activity, type II
growth factor binding
inhibin binding
metal ion binding
activin binding