8256

• Gene Symbol: MEFV
• Gene Name: Mediterranean fever
• Gene Aliases: FMF, MEF, TRIM20
• Chromosome Location: Chr.16: 3242028 - 3256776 on Build GRCh38
• UniGene ID: Hs.632221
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MEFV
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000243.2	NP_000234.1	10	3006
	NM_001198536.1	NP_001185465.1	9	2548
GenBank mRNA	AF018080.1	-	10	3007

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

inflammatory response
positive regulation of autophagy
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
response to interferon-gamma
negative regulation of inflammatory response
negative regulation of macrophage inflammatory protein 1 alpha production
negative regulation of cytokine production involved in inflammatory response
negative regulation of NLRP3 inflammasome complex assembly
positive regulation of cysteine-type endopeptidase activity

Function(s)

actin binding
protein binding
zinc ion binding