83961

• Gene Symbol: Smurf1
• Gene Name: SMAD specific E3 ubiquitin protein ligase 1
• Gene Aliases: 4930431E10Rik, mKIAA1625
• Chromosome Location: Chr.5: 144876495 - 144965830 on Build GRCm38
• UniGene ID: Mm.27735
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smurf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001038627.1	NP_001033716.1	15, 16	2083
	NM_029438.3	NP_083714.3	15, 16	2083
GenBank mRNA	AK015264.1	-	11, 12	1482
	AK034736.1	-	6, 7	681
	AK122534.1	-	4, 5	458
	AK154491.1	-	15, 16	2084
	BC029097.1	-	15, 16	2111	3660965

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109598, XM_006248882, XM_008769002.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
positive regulation of defense response to virus by host
protein export from nucleus
transforming growth factor beta receptor signaling pathway
protein ubiquitination
cell differentiation
negative regulation of ossification
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
receptor catabolic process
protein localization to cell surface
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein targeting to vacuole involved in autophagy
mitophagy in response to mitochondrial depolarization
positive regulation of dendrite extension
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
ubiquitin protein ligase activity
I-SMAD binding
R-SMAD binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity