85077

• Gene Symbol: Il23a
• Gene Name: interleukin 23, alpha subunit p19
• Gene Aliases: IL-23, p19
• Chromosome Location: Chr.10: 128296140 - 128298084 on Build GRCm38
• UniGene ID: Mm.125482
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Il23a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031252.2	NP_112542.1	4	833
GenBank mRNA	AF301619.1	-	4	833
	BC019953.1	-	4	817	3708687

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_130410, BC098907.

Panther Classification:

Molecular Function -

cytokine, interleukin superfamily, intercellular signal molecule

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
positive regulation of defense response to virus by host
immune system process
positive regulation of T-helper 1 type immune response
inflammatory response
immune response
positive regulation of activation of JAK2 kinase activity
negative regulation of interleukin-10 production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-17 production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell proliferation
T cell proliferation
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat4 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of memory T cell differentiation
innate immune response
positive regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
tissue remodeling
defense response to Gram-negative bacterium
positive regulation of NK T cell activation
positive regulation of NK T cell proliferation
defense response to virus
positive regulation of neutrophil chemotaxis
positive regulation of T-helper 17 type immune response
positive regulation of T-helper 17 cell lineage commitment

Function(s)

cytokine activity
protein binding
interleukin-23 receptor binding