85281

• Gene Symbol: Dock2
• Gene Name: dedicator of cyto-kinesis 2
• Gene Aliases: AI662014, AW122239, CED-5, Hch, MBC
• Chromosome Location: Chr.11: 34226815 - 34514545 on Build GRCm38
• UniGene ID: Mm.380679
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dock2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_033374.3	NP_203538.2		291
GenBank mRNA	AK037611.1	-		279
	AK089228.1	-		279
	AK089682.1	-		270
	AY027438.1	-		209

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767630, BC101877.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
cytoskeleton organization
small GTPase mediated signal transduction
positive regulation of Rac protein signal transduction
T cell proliferation
T cell activation
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell activation
alpha-beta T cell proliferation
positive regulation of phagocytosis

Function(s)

guanyl-nucleotide exchange factor activity
GTPase activator activity
Rac guanyl-nucleotide exchange factor activity
T cell receptor binding