861

• Gene Symbol: PNKP
• Gene Name: polynucleotide kinase 3'-phosphatase
• Gene Aliases: AOA4, EIEE10, MCSZ, PNK
• Chromosome Location: Chr.19: 49861203 - 49867565 on Build GRCh38
• UniGene ID: Hs.78016
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PNKP
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007254.3	NP_009185.2	11	1093
GenBank mRNA	AF120499.1	-	11	1083
	AF125807.1	-	10	983
	AF126486.1	-	10	983
	BC002519.2	-	10	941	3140712
	BC033822.1	-	11	1089	5218400

More Information

Gene Ontology Categories:

Process(es)

nucleotide-excision repair, DNA damage removal
DNA-dependent DNA replication
DNA repair
response to oxidative stress
response to radiation
dephosphorylation
positive regulation of telomere maintenance via telomerase
DNA damage response, detection of DNA damage
nucleotide phosphorylation
positive regulation of telomerase activity
nucleic acid phosphodiester bond hydrolysis
DNA 3' dephosphorylation involved in DNA repair
polynucleotide 3' dephosphorylation
positive regulation of telomere capping

Function(s)

damaged DNA binding
double-stranded DNA binding
endonuclease activity
protein binding
ATP binding
purine nucleotide binding
nucleotide kinase activity
polynucleotide 3'-phosphatase activity
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity