86388

• Gene Symbol: Tlr3
• Gene Name: toll-like receptor 3
• Gene Aliases: AI957183
• Chromosome Location: Chr.8: 45395665 - 45411949 on Build GRCm38
• UniGene ID: Mm.33874
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tlr3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_126166.4	NP_569054.2	6	1274
GenBank mRNA	AF355152.1	-	4	956
	AF420279.1	-	3	913
	AK083977.1	-	6	1275
	AK166177.1	-	5	1149
	AK171438.1	-	6	1256
	BC099937.1	-	6	1312	30084049

More Information

Gene Ontology Categories:

Process(es)

microglial cell activation
positive regulation of cytokine production
positive regulation of protein phosphorylation
toll-like receptor signaling pathway
microglial cell activation involved in immune response
immune system process
regulation of dendritic cell cytokine production
MyD88-independent toll-like receptor signaling pathway
defense response
inflammatory response
signal transduction
I-kappaB phosphorylation
response to virus
positive regulation of type I interferon production
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
toll-like receptor 3 signaling pathway
positive regulation of type III interferon production
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
response to dsRNA
positive regulation of interferon-gamma biosynthetic process
positive regulation of chemokine biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
cellular response to exogenous dsRNA
extrinsic apoptotic signaling pathway
necroptotic signaling pathway

Function(s)

RNA binding
double-stranded RNA binding
receptor activity
transmembrane signaling receptor activity
protein binding
identical protein binding