8658

• Gene Symbol: IGFBP3
• Gene Name: insulin like growth factor binding protein 3
• Gene Aliases: BP-53, IBP3
• Chromosome Location: Chr.7: 45912245 - 45921272 on Build GRCh38
• UniGene ID: Hs.450230
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IGFBP3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000598.4	NP_000589.2	1, 2	543
	NM_001013398.1	NP_001013416.1	1, 2	561
	XM_017012152.1	XP_016867641.1	1, 2	542
GenBank mRNA	AK055632.1	-	2, 3	491
	AK056274.1	-	2, 3	415
	AK075483.1	-	2, 3	456
	AK091706.1	-	2, 3	286
	AK091745.1	-	3, 4	356
	AK092447.1	-	3, 4	371
	AK095408.1	-	2, 3	430
	AK095869.1	-	2, 3	387
	AK095900.1	-	2, 3	399
	AK095907.1	-	2, 3	409
	AK095974.1	-		237
	AK095991.1	-	2, 3	387
	AK097201.1	-		79
	AK122873.1	-	2, 3	474
	AK123735.1	-	1, 2	185
	AK125224.1	-	2, 3	252
	AK127537.1	-	2, 3	371
	AK297767.1	-	2, 3	498
	AK298143.1	-	2, 3	408
	AK315668.1	-	1, 2	543
	BC000013.2	-	1, 2	509	3506666
	BC018962.2	-	1, 2	489	3506929
	BC064987.1	-	1, 2	527	4850456
	DQ884396.1	-	2, 3	282
	DQ884397.1	-	2, 3	348
	DQ884398.1	-	2, 3	327
	M31159.1	-	1, 2	520
	X64875.1	-	1, 2	543

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

regulation of cell growth
osteoblast differentiation
negative regulation of protein phosphorylation
protein phosphorylation
apoptotic process
negative regulation of cell proliferation
negative regulation of signal transduction
regulation of glucose metabolic process
negative regulation of smooth muscle cell migration
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of MAPK cascade
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of insulin-like growth factor receptor signaling pathway
cellular protein metabolic process
type B pancreatic cell proliferation
positive regulation of myoblast differentiation
negative regulation of smooth muscle cell proliferation

Function(s)

fibronectin binding
protein binding
insulin-like growth factor binding
protein tyrosine phosphatase activator activity
insulin-like growth factor I binding
insulin-like growth factor II binding
metal ion binding