8678

• Gene Symbol: NOS2
• Gene Name: nitric oxide synthase 2
• Gene Aliases: HEP-NOS, INOS, NOS, NOS2A
• Chromosome Location: Chr.17: 27756766 - 27804339 on Build GRCh38
• UniGene ID: Hs.709191
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000625.4	NP_000616.3	3	395
	XM_011524859.2	XP_011523161.1	3	421
	XM_011524860.2	XP_011523162.1	2	214
	XM_011524861.1	XP_011523163.1	3	393
	XM_011524862.1	XP_011523164.1	2	141
GenBank mRNA	AB022318.1	-	2	131
	AF068236.1	-	3	365
	AK304252.1	-	3	393
	BC130283.1	-	3	315	40146314
	BC144126.1	-	3	315	9052646
	D26525.1	-	2	145
	L09210.1	-	3	337
	L24553.1	-	2	207
	U05810.1	-	3	325
	U20141.1	-	2	131
	U31511.1	-	3	236
	X73029.1	-	3	356

More Information

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of leukocyte mediated cytotoxicity
innate immune response in mucosa
arginine catabolic process
superoxide metabolic process
nitric oxide biosynthetic process
nitric oxide mediated signal transduction
circadian rhythm
response to bacterium
negative regulation of gene expression
peptidyl-cysteine S-nitrosylation
positive regulation of guanylate cyclase activity
prostaglandin secretion
cellular response to drug
regulation of cell proliferation
negative regulation of protein catabolic process
defense response to bacterium
regulation of cellular respiration
cell redox homeostasis
negative regulation of blood pressure
positive regulation of vasodilation
regulation of insulin secretion
defense response to Gram-negative bacterium
positive regulation of killing of cells of other organism
oxidation-reduction process
cellular response to lipopolysaccharide
cellular response to interferon-gamma
interleukin-6 secretion
interleukin-8 secretion
regulation of cytokine production involved in inflammatory response

Function(s)

nitric-oxide synthase activity
receptor binding
protein binding
calmodulin binding
FMN binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding