87258

• Gene Symbol: Pxn
• Gene Name: paxillin
• Gene Aliases: AW108311, AW123232, Pax
• Chromosome Location: Chr.5: 115506674 - 115555987 on Build GRCm38
• UniGene ID: Mm.18714
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pxn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011223.3	NP_035353.1	8	1307
	NM_133915.3	NP_598676.2	9	1409
GenBank mRNA	AF293882.1	-	8	1232
	AF293883.1	-	8	1229
	AK148060.1	-	8	1293
	AK149933.1	-	8	1272
	AK167299.1	-	8	1246
	AK171226.1	-	8	1295
	AK171436.1	-	8	1272
	BC003298.1	-	4	590
	BC025493.1	-	8	1265

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012147, XM_006249455, XM_006249460, XM_006249459, XM_006249457, and others.

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
movement of cell or subcellular component
cytoskeleton organization
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
peptidyl-tyrosine phosphorylation
lamellipodium assembly
substrate adhesion-dependent cell spreading
positive regulation of protein kinase activity
focal adhesion assembly
branching morphogenesis of an epithelial tube
growth hormone receptor signaling pathway

Function(s)

integrin binding
protein binding
beta-catenin binding
zinc ion binding
vinculin binding
protein kinase binding
receptor signaling complex scaffold activity
protein complex binding
metal ion binding
BH4 domain binding