8755

• Gene Symbol: HGF
• Gene Name: hepatocyte growth factor
• Gene Aliases: DFNB39, F-TCF, HGFB, HPTA, SF
• Chromosome Location: Chr.7: 81699006 - 81770438 on Build GRCh38
• UniGene ID: Hs.396530
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HGF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000601.5	NP_000592.3	2	470
	NM_001010931.2	NP_001010931.1	2	470
	NM_001010932.2	NP_001010932.1	2	470
	NM_001010933.2	NP_001010933.1	2	470
	NM_001010934.2	NP_001010934.1	2	470
	XM_006715956.2	XP_006716019.1	3	433
	XM_011516115.2	XP_011514417.1	3	433
	XM_017012097.1	XP_016867586.1	3	433
	XM_017012098.1	XP_016867587.1	3	433
GenBank mRNA	AB208900.1	-	2	377
	AK291674.1	-	2	405
	AK313694.1	-	2	320
	BC022308.1	-	2	319
	BC063485.1	-	2	328
	BC105797.1	-	2	410
	BC130284.1	-	2	318	40146315
	BC130286.1	-	2	318	40146317
	BU533235.1	-		409
	FJ830861.1	-	2	243
	FJ830862.1	-	2	243
	L02931.1	-	2	303
	M29145.1	-	2	344
	M55379.1	-	2	243
	M60718.1	-	2	315
	M73239.1	-	2	308
	M73240.1	-	2	308
	M77227.1	-	2	325
	U46010.1	-	2	297
	X57574.1	-	2	320

More Information

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

activation of MAPK activity
epithelial to mesenchymal transition
liver development
platelet degranulation
proteolysis
mitotic nuclear division
positive regulation of cell proliferation
negative regulation of autophagy
positive regulation of phosphatidylinositol 3-kinase signaling
hyaluronan metabolic process
positive regulation of cell migration
organ regeneration
positive regulation of myelination
negative regulation of interleukin-6 production
positive regulation of interleukin-10 production
negative regulation of peptidyl-serine phosphorylation
cellular response to hepatocyte growth factor stimulus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
hepatocyte growth factor receptor signaling pathway
negative regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
myoblast proliferation
cell chemotaxis
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
positive regulation of neuron projection regeneration
negative regulation of release of cytochrome c from mitochondria
regulation of p38MAPK cascade
negative regulation of hydrogen peroxide-mediated programmed cell death
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of tau-protein kinase activity
positive regulation of DNA biosynthetic process

Function(s)

serine-type endopeptidase activity
protein binding
growth factor activity
chemoattractant activity
protein heterodimerization activity