8767

• Gene Symbol: IGF1
• Gene Name: insulin like growth factor 1
• Gene Aliases: IGF-I, IGFI, MGF
• Chromosome Location: Chr.12: 102395867 - 102481839 on Build GRCh38
• UniGene ID: Hs.160562
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IGF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000618.4	NP_000609.1	3, 4	674
	NM_001111283.2	NP_001104753.1	4, 5	723
	NM_001111284.1	NP_001104754.1	3, 4	512
	XM_017019262.1	XP_016874751.1	4, 5	533
	XM_017019263.1	XP_016874752.1	3, 4	476
GenBank mRNA	AB209184.1	-	3, 4	625
	AK312231.1	-	3, 4	573
	BC152321.1	-	3, 4	555	40129266
	CR541861.1	-	3, 4	410
	M27544.1	-	3, 4	558
	M29644.1	-	3, 4	421
	M37484.1	-	3, 4	512
	U40870.1	-	3, 4	402
	X00173.1	-	3, 4	421
	X56773.1	-	3, 4	410
	X57025.1	-	3, 4	576

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010512, NM_001111276, NM_001111275, NM_001111274, CT010364, and others.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
skeletal system development
response to hypoxia
cell activation
platelet degranulation
DNA replication
regulation of translation
movement of cell or subcellular component
signal transduction
Ras protein signal transduction
muscle organ development
female pregnancy
aging
response to nutrient
memory
cell proliferation
positive regulation of cell proliferation
response to heat
glycolate metabolic process
regulation of gene expression
positive regulation of glycoprotein biosynthetic process
positive regulation of cardiac muscle hypertrophy
phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
response to activity
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
muscle hypertrophy
myotube cell development
positive regulation of smooth muscle cell migration
proteoglycan biosynthetic process
positive regulation of cell migration
response to caffeine
activation of protein kinase B activity
response to lipopolysaccharide
cellular response to insulin stimulus
positive regulation of protein import into nucleus, translocation
negative regulation of smooth muscle cell apoptotic process
response to nicotine
bone mineralization involved in bone maturation
regulation of multicellular organism growth
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of apoptotic process
positive regulation of DNA binding
positive regulation of MAPK cascade
protein kinase B signaling
positive regulation of insulin-like growth factor receptor signaling pathway
cellular protein metabolic process
myoblast differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
positive regulation of Ras protein signal transduction
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of protein secretion
positive regulation of peptidyl-tyrosine phosphorylation
protein stabilization
detection of mechanical stimulus involved in sensory perception
response to glucocorticoid
myoblast proliferation
regulation of calcium ion transport
negative regulation of oocyte development
positive regulation of cell growth involved in cardiac muscle cell development
ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to electrical stimulus
cellular response to estradiol stimulus
negative regulation of release of cytochrome c from mitochondria
negative regulation of neuron death
positive regulation of trophectodermal cell proliferation
negative regulation of cholangiocyte apoptotic process
positive regulation of transcription regulatory region DNA binding
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

insulin receptor binding
insulin-like growth factor receptor binding
integrin binding
hormone activity
steroid binding
protein binding
growth factor activity