89037

• Gene Symbol: Nkx6-1
• Gene Name: NK6 homeobox 1
• Gene Aliases: NKX6A, Nkx6.1
• Chromosome Location: Chr.5: 101659184 - 101664711 on Build GRCm38
• UniGene ID: Mm.193072
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nkx6-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_144955.2	NP_659204.1	2	1164
GenBank mRNA	AF357883.1	-	2	1164
	BC138019.1	-	2	1070	8861038
	BC138020.1	-	2	1070	8861039

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_006168.
This siRNA also targets the following transcripts in Rat: NM_031737, AF004431.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
smoothened signaling pathway
multicellular organism development
cell proliferation
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
central nervous system neuron differentiation
neurogenesis
cell differentiation
regulation of axon extension
endocrine pancreas development
positive regulation of insulin secretion
positive regulation of neuron differentiation
negative regulation of glial cell differentiation
positive regulation of glial cell differentiation
oligodendrocyte differentiation
regulation of neuron migration

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding