90227

• Gene Symbol: Nlrp3
• Gene Name: NLR family, pyrin domain containing 3
• Gene Aliases: AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS, Mmig1, NALP3, Pypaf1
• Chromosome Location: Chr.11: 59541569 - 59566956 on Build GRCm38
• UniGene ID: Mm.54174
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nlrp3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_145827.3	NP_665826.1	2, 3	495
GenBank mRNA	AF486632.1	-	3, 4	391
	AY337285.1	-	1, 2	281
	AY355340.1	-	1, 2	269
	AY495376.1	-	2, 3	495
	AY495377.1	-	3, 4	391
	BC116174.1	-	2, 3	455	40048724
	BC116175.1	-	2, 3	455	40048725
	KF032621.1	-	1, 2	271

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191642, XM_006246457, XM_006246458, XM_006246453, XM_006246455, and others.

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

negative regulation of acute inflammatory response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
negative regulation of NF-kappaB transcription factor activity
interleukin-1 beta production
interleukin-18 production
negative regulation of NF-kappaB import into nucleus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
NLRP3 inflammasome complex assembly
interleukin-1 secretion
negative regulation of interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
negative regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
cellular response to lipopolysaccharide

Function(s)

nucleotide binding
protein binding
ATP binding