92467

• Gene Symbol: Mkl1
• Gene Name: MKL (megakaryoblastic leukemia)/myocardin-like 1
• Gene Aliases: AMKL, Bsac, Mal, Mrtf-A
• Chromosome Location: Chr.15: 81012281 - 81190757 on Build GRCm38
• UniGene ID: Mm.439814
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mkl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001082536.1	NP_001076005.1	3, 4	575
	NM_153049.3	NP_694629.2	2, 3	337
GenBank mRNA	AF385582.1	-	2, 3	108
	AF532597.1	-	3, 4	459
	AK044188.1	-	3, 4	568
	AK089416.1	-	1, 2	167
	AK154561.1	-	3, 4	555
	AK155821.1	-	3, 4	577
	AK155937.1	-	2, 3	321
	AK157985.1	-	1, 2	186
	BB850443.1	-	2, 3	320
	BC050941.1	-	3, 4	468	6821370
	BC054801.1	-	3, 4	511
	BY200528.1	-	2, 3	310
	BY208699.1	-	2, 3	338
	BY749697.1	-	1, 2	167
	BY750304.1	-	3, 4	577

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_020831, BC139730, AB037859, AJ297258, BC115039, and others.
This siRNA also targets the following transcripts in Rat: XM_008765806, XM_235497, XM_003750385, XM_006242130, AB588920, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of transcription via serum response element binding
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
actin binding
actin monomer binding
protein binding
leucine zipper domain binding