942

• Gene Symbol: EIF2AK1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: HCR, HRI
• Chromosome Location: Chr.7: 6022247 - 6059229 on Build GRCh38
• UniGene ID: Hs.520205
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EIF2AK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001134335.1	NP_001127807.1	2, 3	421
	NM_014413.3	NP_055228.2	2, 3	421
GenBank mRNA	AB037790.1	-	2, 3	346
	AF100784.1	-	2, 3	310
	AF147094.1	-	2, 3	356
	AF183414.1	-	2, 3	308
	AF255050.1	-	2, 3	366
	AK075192.1	-	2, 3	349
	AK290327.1	-	2, 3	354
	AL136563.1	-	2, 3	326
	AL834494.1	-	2, 3	326
	BC006524.2	-	2, 3	353	2989989
	DC341983.1	-	2, 3	421

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
phagocytosis
response to stress
negative regulation of cell proliferation
response to external stimulus
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
macrophage differentiation
negative regulation of translational initiation by iron
protoporphyrinogen IX metabolic process
protein autophosphorylation
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

eukaryotic translation initiation factor 2alpha kinase activity
ATP binding
heme binding
protein homodimerization activity