9727

Gene Symbol:

AKR1C1 AKR1C3

Gene Name:

aldo-keto reductase family 1 member C1

aldo-keto reductase family 1, member C3

Gene Aliases:

2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB

DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS

Chromosome Location:

Chr.10: 4963262 - 4979967 on Build GRCh38

Chromosome Location:

Chr.10: 5048766 - 5107686 on Build GRCh38

UniGene ID:

Hs.460260

Hs.78183

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: AKR1C1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001353.5	NP_001344.2	2	299
	XM_017015791.1	XP_016871280.1	2	169
GenBank mRNA	AB031083.1	-	2	116
	AK303435.1	-	2	142
	AK310658.1	-	2	146
	BC015490.2	-	2	133	3877178
	BC020216.1	-	2	132	4662654
	BC040210.1	-	7	958	4825338
	BM923712.1	-	2	148
	BT007197.1	-	2	116
	D26124.1	-	2	67
	M86609.1	-	2	122
	S68290.1	-	2	107
	U05684.1	-	2	119

Gene Symbol: AKR1C3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	DQ269985.1	-	2	116

More Information

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

retinoid metabolic process
xenobiotic metabolic process
digestion
bile acid metabolic process
bile acid and bile salt transport
intestinal cholesterol absorption
epithelial cell differentiation
progesterone metabolic process
retinal metabolic process
cholesterol homeostasis
daunorubicin metabolic process
doxorubicin metabolic process
response to organophosphorus
protein homooligomerization
oxidation-reduction process
cellular response to jasmonic acid stimulus

Function(s)

alditol:NADP+ 1-oxidoreductase activity
aldo-keto reductase (NADP) activity
protein binding
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
phenanthrene 9,10-monooxygenase activity
carboxylic acid binding
bile acid binding
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
androsterone dehydrogenase (B-specific) activity
ketosteroid monooxygenase activity
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
indanol dehydrogenase activity