HSS101059

• Gene Symbol: BMP7
• Gene Name: bone morphogenetic protein 7
• Gene Aliases: OP-1
• Chromosome Location: Chr.20: 57168753 - 57266651 on Build GRCh38
• UniGene ID: Hs.473163
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BMP7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001719.2	NP_001710.1	6	1629
GenBank mRNA	AK094784.1	-	2	369
	AK291186.1	-	6	1205
	AK312419.1	-	6	1202
	BC008584.1	-	6	1141	4183402
	EU679366.1	-	6	1013
	KJ875974.1	-	3	224
	M60316.1	-	6	1196
	X51801.1	-	6	1222

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191856, AF100787, D29769.
This siRNA also targets the following transcripts in Mouse: NM_007557, X56906, BC010771, CA316109.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

skeletal system development
ossification
metanephros development
ureteric bud development
mesoderm formation
mesonephros development
epithelial to mesenchymal transition
axon guidance
embryonic pattern specification
negative regulation of striated muscle cell apoptotic process
positive regulation of peptidyl-threonine phosphorylation
positive regulation of pathway-restricted SMAD protein phosphorylation
dendrite development
embryonic limb morphogenesis
positive regulation of bone mineralization
BMP signaling pathway
epithelial cell differentiation
negative regulation of NF-kappaB transcription factor activity
response to estradiol
response to vitamin D
positive regulation of heterotypic cell-cell adhesion
protein localization to nucleus
growth
negative regulation of phosphorylation
negative regulation of NF-kappaB import into nucleus
odontogenesis of dentin-containing tooth
regulation of apoptotic process
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
negative regulation of MAP kinase activity
response to peptide hormone
negative regulation of neuron differentiation
positive regulation of osteoblast differentiation
negative regulation of Notch signaling pathway
negative regulation of cell cycle
negative regulation of mitotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic camera-type eye morphogenesis
branching morphogenesis of an epithelial tube
mesenchymal cell differentiation
neuron projection morphogenesis
cartilage development
embryonic skeletal joint morphogenesis
regulation of pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
branching involved in salivary gland morphogenesis
mesenchyme development
negative regulation of cell death
negative regulation of prostatic bud formation
regulation of branching involved in prostate gland morphogenesis
monocyte aggregation
cellular response to hypoxia
cellular response to BMP stimulus
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
negative regulation of glomerular mesangial cell proliferation
metanephric mesenchyme morphogenesis
nephrogenic mesenchyme morphogenesis
metanephric mesenchymal cell proliferation involved in metanephros development
positive regulation of dendrite development
positive regulation of hyaluranon cable assembly
regulation of removal of superoxide radicals

Function(s)

cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
heparin binding
BMP receptor binding