HSS101720

• Gene Symbol: CDK2
• Gene Name: cyclin dependent kinase 2
• Gene Aliases: CDKN2, p33(CDK2)
• Chromosome Location: Chr.12: 55966769 - 55972789 on Build GRCh38
• UniGene ID: Hs.19192
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290230.1	NP_001277159.1	2, 3	477
	NM_001798.4	NP_001789.2	3, 4	555
	NM_052827.3	NP_439892.2	3, 4	555
	XM_011537732.1	XP_011536034.1	3, 4	555
GenBank mRNA	AB012305.1	-	3, 4	317
	AK291941.1	-	3, 4	494
	AK293246.1	-	2, 3	416
	BC003065.2	-	3, 4	475	3504348
	BJ991087.1	-	3, 4	552
	BT006821.1	-	3, 4	315
	M68520.1	-	3, 4	505
	X61622.1	-	3, 4	315
	X62071.1	-	3, 4	485

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_199501, XM_006240778, BC061832, D28753.
This siRNA also targets the following transcripts in Mouse: NM_183417, NM_016756, U63337, AK184593, AK189612, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
lens development in camera-type eye
DNA replication
DNA repair
potassium ion transport
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic nuclear division
centriole replication
meiotic nuclear division
Ras protein signal transduction
positive regulation of cell proliferation
response to toxic substance
histone phosphorylation
peptidyl-serine phosphorylation
organ regeneration
mitotic G1 DNA damage checkpoint
positive regulation of DNA-dependent DNA replication initiation
response to estradiol
cellular response to insulin stimulus
response to drug
response to ethanol
positive regulation of transcription, DNA-templated
response to cadmium ion
centrosome duplication
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
response to cAMP
response to electrical stimulus
regulation of gene silencing
cellular response to nitric oxide
regulation of signal transduction by p53 class mediator

Function(s)

protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
cyclin binding
protein complex binding
histone kinase activity
metal ion binding