HSS103100

• Gene Symbol: EGF
• Gene Name: epidermal growth factor
• Gene Aliases: HOMG4, URG
• Chromosome Location: Chr.4: 109912883 - 110013079 on Build GRCh38
• UniGene ID: Hs.419815
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EGF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001178130.2	NP_001171601.1	21, 22	3617
	NM_001178131.2	NP_001171602.1	21, 22	3614
	NM_001963.5	NP_001954.2	22, 23	3740
	XM_005262796.2	XP_005262853.1	22, 23	3741
	XM_011531707.1	XP_011530009.1	23, 24	3390
	XM_017007845.1	XP_016863334.1	22, 23	3765
	XM_017007846.1	XP_016863335.1	22, 23	3765
	XM_017007847.1	XP_016863336.1	21, 22	3642
	XM_017007848.1	XP_016863337.1	21, 22	3639
	XM_017007849.1	XP_016863338.1	20, 21	3522
GenBank mRNA	AK299306.1	-	21, 22	3616
	BC093731.1	-	22, 23	3383	7939576
	BC113461.1	-	22, 23	3383	8322513
	BC143357.1	-	21, 22	3261
	X04571.1	-	22, 23	3724

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
activation of MAPK activity
angiogenesis
platelet degranulation
DNA replication
signal transduction
activation of transmembrane receptor protein tyrosine kinase activity
epidermal growth factor receptor signaling pathway
STAT protein import into nucleus
positive regulation of cell proliferation
positive regulation of peptidyl-threonine phosphorylation
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
positive regulation of cerebellar granule cell precursor proliferation
positive regulation of catenin import into nucleus
ERBB2 signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
positive regulation of phosphorylation
positive regulation of DNA binding
positive regulation of MAP kinase activity
positive regulation of GTPase activity
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of epidermal growth factor-activated receptor activity
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
branching morphogenesis of an epithelial tube
negative regulation of secretion
canonical Wnt signaling pathway
mammary gland alveolus development
ERK1 and ERK2 cascade
regulation of calcium ion import
negative regulation of cholesterol efflux
positive regulation of hyaluronan biosynthetic process
regulation of protein localization to cell surface
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
regulation of cell motility

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
calcium ion binding
protein binding
growth factor activity
Wnt-protein binding
transmembrane receptor protein tyrosine kinase activator activity
Wnt-activated receptor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity