HSS103351

• Gene Symbol: ERCC4
• Gene Name: ERCC excision repair 4, endonuclease catalytic subunit
• Gene Aliases: ERCC11, FANCQ, RAD1, XFEPS, XPF
• Chromosome Location: Chr.16: 13920138 - 13952348 on Build GRCh38
• UniGene ID: Hs.567265
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ERCC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005236.2	NP_005227.1	8, 9	1823
	XM_011522424.2	XP_011520726.1	9, 10	1980
	XM_011522427.1	XP_011520729.1	3, 4	960
	XM_017023043.1	XP_016878532.1	9, 10	1937
GenBank mRNA	AK289726.1	-	8, 9	1822
	AK301930.1	-	3, 4	1092
	U64315.1	-	8, 9	1796

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_015769, BC026792, CD352377, AF189285, CX210668.

Panther Classification:

Molecular Function -

DNA metabolism protein, endodeoxyribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

resolution of meiotic recombination intermediates
telomere maintenance
double-strand break repair via homologous recombination
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
response to UV
UV protection
negative regulation of telomere maintenance
nucleotide-excision repair, DNA incision
cellular response to UV
interstrand cross-link repair
global genome nucleotide-excision repair
nucleotide-excision repair involved in interstrand cross-link repair

Function(s)

single-stranded DNA endodeoxyribonuclease activity
TFIID-class transcription factor binding
damaged DNA binding
single-stranded DNA binding
endodeoxyribonuclease activity
protein binding
protein C-terminus binding
structure-specific DNA binding
protein N-terminus binding